I want to encapsulate a drug or peptide.
Thank you so much for your help!
I am working on the production of composite system of polymer and drug. My aim now is to produce microparticles of coprecipitates of drug and polymer. I usually demonstrate that drug is inside my...
31 December 2016 9,632 8 View
Someone can suggest me some articles about uses of this drug. Thank you!
03 April 2015 4,061 6 View
I produced powder of a polymer and curcumin and I want to study the release of curcumin (or luteolin) by Uv-vis. Curcumin is hydrophobic, so I have some problem to built a calibration curve in...
03 April 2015 9,297 9 View
I know it is soluble in ethanol, acetone, DMSO, DMF; someone knows about chloroform?
02 March 2015 7,909 2 View
I want to demonstrate that FITC is present in a powder obtained by the micronization method.
02 March 2015 1,282 3 View
I want to dissolve dextran in a mixture of water/Ethanol.
01 February 2015 3,532 8 View
I want to use curcumin as model drug. Is the same if I use curcuma bought in an herbal medicine?
31 December 2014 8,161 1 View
I want to determine a loading of a substance into a powder.
31 December 2014 1,446 2 View
Read 2 answers by scientists with 1 recommendation from their colleagues to the question asked by Alessia Di Capua on Jan 3, 2015
31 December 2014 5,396 1 View
I need a drug which is soluble in water.
31 December 2014 1,724 4 View
We intend to study the interaction between peptides and polymer (like PP, PE and PS) through MD simulations using Martini force fields ( Martini 2 for PP and Martini 3 for PE, PS). We have...
08 August 2024 4,842 0 View
I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...
07 August 2024 2,283 2 View
Hi, we have measured tryptic peptides using both DDA and DIA method on QExactive. In DDA replicates i saw unusual intensity drops occurring at the same sections of chromatograms in DDA replicates...
07 August 2024 3,218 4 View
Hello, I am currently analyzing some phosphoproteomics data, but I have peptides with multiple phosphorylation sites or phosphorylations together with carbamidomethylation or oxidation. How can I...
04 August 2024 8,432 3 View
I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...
03 August 2024 4,725 2 View
Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...
03 August 2024 2,730 1 View
Recently I'm trying to use Sep-pack C18 1 cc Vac Cartridge (Waters: SKU: WAT054955) to desalt digested peptides. However, the recovery rate is usually 40-60%. What is the normal recovery rate?
31 July 2024 6,544 11 View
I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...
24 July 2024 8,696 0 View
Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...
19 July 2024 2,155 0 View
So i have a few peptides (synthesized by SPPS and not cleaved from resin) and I want to add a maleimide label. We have NHS-PEG-Maleimide and from literature it is evident that the free amine group...
18 July 2024 4,075 3 View
