use the Pimecrolimus

Class: Skin and Mucous Membrane Agents, Miscellaneous

VA Class: DE900

Chemical Name: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS) - 3 - [(1E) - 2 - [(1R,3R,4S) - 4 - Chloro - 3 - methoxycyclohexyl] - 1 - methyl - ethenyl] - 8 - ethyl - 5,6,8,11,12,13,14,15,16,17,18,19,24,26,26a - hexadecahydro - 5,19 - dihydroxy - 14,16 - dimethoxy - 4,10,12,18 - tetramethyl - 15,19 - epoxy - 3H - pyrido[2,1 - c][1,4]oxaazacyclotricosine - 1,17,20,21(4H,23H) - tetrone

Molecular Formula: C43H68ClNO11

CAS Number: 137071-32-0

Brands: Elidel

thanks sir for your reply.....

Which drug can i use as reference for immunomodulatory activity?

Which One enhances the immune response?

You can use cyclophosphamide i.p.; 100-200mg/kg; daily for 4 days. This treatment induce lymphopenia in mice, depleting even Tregs.

Rapamycin would work!