It depends! I know that the US National Cancer Institute can make some tests on your products, but only to understand the effectivness of your compounds against over 60 different type of cancer cell lines. This is the web page: http://dtp.nci.nih.gov/branches/btb/ivclsp.html

First depends upon What activity you want, and first check SAR of your compounds then go for activity which is supposed to be present in that

Its also depends on Which activities you want to do and Which type of your compounds?

hi pragna,

there are some company of services that test the molecules to find biological activity...one of these is the INC research...However, these kind of studies are very very expencive...I suggest you to search in leceterature the group of research that work on the receptort of your interest...than you can try to contat them for free collaboration...this way is not easy but can be useful.

"What kind of biological properties your synthesized compounds exhibit"? It can be understood by a simple literature survey. for the next step, you should locate nearest universities and research institutes having facilities to perform this kind of activities then collaborate with them (easiest way).

The more difficult way is to do literature review at first step and try to contact to corresponding authors of the papers you have found and ask them collaborate. It is so time consuming and a bit tricky, but possible!

Good luck!

Dr Dhanji Rajani, Microcare Lab., Surat

You can send it at ACTREC Mumbai for anticancer activity with Rs. 2000 for a set of 5 samples in one cell lines.

You can send your newly synthesized centre for testing to KLE societies  college of Pharmacy , Belgum.

Dear Madam,

Congrats for the preparation of novel organic compounds. Some of the researcher mentioned above, Kindly review the literature regarding your synthesized compounds. Check out the similarities with structure & functional group.

More importantly I would like suggest you for insilico methods like PASS online software which will give the probable biological activities for your synthesized compounds. It is free online software. Regarding the same kindly overlook my publication.

Please find the attachment of related research article for further perusal. In my view PASS software/ Lazar Toxicity will definitely provide the idea of bio activities for your synthesized compounds.

Internet version of PASS and Pharma Expert:

http://www.ibmc.msk.ru/PASS.

1) Anticancer Study: http://www.actrec.gov.in/ & [email protected]

2) Anti-TB Study: [email protected]

3) Antimicrobial Study: [email protected]

                                         Best Wishes,

                                    Dr. Mayur M. Aitawade

Thank you all for your valuable advice.

Other in silico method is molinspiration, it´s free online software

http://www.molinspiration.com/cgi-bin/properties

Good luck!!!

The suggestions provided are all good;  indeed, one needs to have some sense of the pharmacodynamics of your compounds.  If you for instance are probing antitumor properties, the NCI C-60 cell line is a good option, but one needs to first establish some sort of collaboration.

To,

David P. Brown

Dear Sir,

I Appreciate your answer. In my view it may be risky if we will conduct invivo/invitro anticancer screening without any prediction. It is also expensive.

Try to contact for collaboration. Why I am asking paper writing is very easy.

Thanki,

I can see very supportive answers from our colleagues, however I would like to add mine. First, when you were building your molecules either you had in mind new chemistry or application. So you have some literature in hand about the usefulness of your type of structures. Second, You could approach colleagues in college of pharmacy within your institute or the neighboring ones that you can meet in person and discuss what you need and sign with them collaborative agreement. I find this more realistic and fruitful. Of course, on the long run you could establish the international collaboration after gaining more experience.

Good luck

What type of activity you want to check?

We are launching an initiative for exactly these types of situations, attempting to discover new antibiotics by providing free antimicrobial screening to chemists around the world - particularly targeting unusual chemical structures.  The submitter retains all their rights to the compounds and results.  Please see www.wadi.org for more details, and how to submit compounds.

Just a clarification Mark, I take is this one the web page, is it ?

http://www.wadi.org.au/

Apologies, yes, it should have been www.wadi.org.au

Dear, We have facility like antibacterial, antifungal, antituberculosis and antimalarial

please visit us at www.microcarelab.in

Dr Dhanji Rajani

Surat

You can send your sample to KLE societies College of Pharmacy, Cancer institute Khargar of Hoffkin insrtitute Mumbai.You have to take permission in advance. However they will charge for screening.

For free testing against 5 bacteria and two fungi, please send to the Community for Open Antimicrobial Drug Discovery (CO-ADD) at www.co-add.org (see article describing us in ACS Infectious Disease, http://pubs.acs.org/doi/full/10.1021/acsinfecdis.5b00044)

Article Helping Chemists Discover New Antibiotics