Where I can find the industrial synthesis of the anticancer TAMOXIFEN?

More Iari Varriale's questions See All

How to remove filamentous fungi from the DO and pH probes?

I am working with A.niger in small bioreactors (0.4L) to produce citric acid. For this purpose, the fungi must to be in pellet form. I reached this goal, however I have some biomass attached on...

16 September 2021 7,311 1 View

Can anyone offer advise regarding low A260/A230 and A260/A280 ratios?

I have extracted DNA (proteinase k, chloroform extraction followed by isopropanol and ethanol 70) from a biological fluid and checked its purity with nanodrop: unfortunately the values of these...

23 April 2014 915 3 View

Absence of contaminant nucleic acids when extracting DNA from plant leaves - any thoughts?

I am extracting DNA from leaves taken from a tree growing in the field. I was wondering how I can be sure that DNA extracted comes only from the plant and not from contaminating agents (mainly...

16 April 2014 3,284 3 View

How to obtain a very high amount of plant DNA?

Does anyone have an idea of how much plant tissue (Leaves grounded in liquid nitrogen) should be processed in order to get at least 1 gram of DNA by classical extraction methods (CTAB)?

10 April 2014 8,392 10 View

How to obtain a clear supernatant from plant leaves DNA extraction?

I tried the CTAB protocol and a salting out protocol for DNA extraction from mature leaves of a tree. The supernatant is in both cases dark green and I suppose that DNA solution still contains...

25 March 2014 5,923 6 View

• What the possible Persistent Organic Pollutants and Heavy metals present in fluorspar, sediments, and water bodies around its mining area?

Approximate concentrations are require in compared with the WHO permissible limts

11 August 2024 2,723 1 View

Basis set and input instruction to calculate HOMO and LUMO using Orca for Imidazolium based organic salts?

Hey there, As a synthetic chemist delving into theoretical calculations for my imidazolium-based organic molecules, I would greatly appreciate any guidance on the appropriate input instructions...

09 August 2024 5,444 7 View

How to calculate CCS for Sodiated adduct ions and Multiply Charged Ions?

I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...

08 August 2024 8,329 0 View

Separation of organic acids-HPLC?

Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.

07 August 2024 8,782 3 View

How to convert g/kg Humic acid dose to kg/ha?

I used humic acid at 0.044 g/kg soil in my pot experiment. But finally, I have to recommend kg/ha. Each pot's soil weight was 11 kg. What is the solution?

02 August 2024 7,186 6 View

Some new emerging problems on application of RL for scheduling in IoT networks?

I have seen plenty of existing works on applied Reinforcement Learning (RL) policies for optimized scheduling in IoT networks including Q-learning, DQNs, and the newer ones including PPO for...

01 August 2024 8,754 2 View

How to improve peaks separation in HPLC?

Hi everyone, I'd like to better separate two close peaks coming from a bioconversion sample, I'm currently using a C18 KromaPhase 4,6mm Ø.I. SCHARLAU, particle size (µm): 10, pore size (Å): 100,...

30 July 2024 435 3 View

Inquiry on Maximum Nucleic Acid Volume for 2.5 mL Liposome Solution?

I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...

30 July 2024 6,420 1 View

Hi there, someone has the SeinFit software for windows because I cannot download it?

DOS version.

29 July 2024 6,064 1 View

There is possible way to calculate experimental DOS from the UPS spectrum of the material. How to calculate the DOS from UPS?

Here, I have attached the UPS graph. I'm trying to calculate the DOS/DOVS from the UPS.

29 July 2024 4,971 1 View

Ravindra Vedantham

You need to look into the patent examples rather than journal articles to get industrial synthesis. Further, procedures executed on kilo to multi kilo scale will provide better industrial process. A simple search in SciFinder or Reaxys will serve the purpose.

Teodoro S Kaufman

Pharmaceutical Substances Kleeman Thieme 2000 There you will find the patents covering its synthesis