There seems to be some evidence that steroids may be beneficial if utilised in the early stages of COVID19.Contrast this with the experience from MERS & SARS where their use has been found to be detrimental. The rapidly changing landscape of EBM & Guidelines isn't of much help either. What does the house think of the role of corticosteroids in COVID 19 ?
We will have to be cautious in accepting the results of RECOVERY Trial about the use of dexamethasone in COVID-19 patients until we have the publication of the study. Very important would be the discharge outcome and site of after-care of such COVID-19 surviving patients.
Covid-19 is a mild self-limiting illness that does not require any treatment in the vast majority of cases.
Current evidence based medicine is based on the presumption of significance when P
Dexamethasone is a steroid that has been used since the 1960s to reduce inflammation in a range of conditions, including inflammatory disorders and certain cancers.
The World Health Organization (WHO) welcomes the initial clinical trial results from the United Kingdom (UK) that show dexamethasone, a corticosteroid, can be lifesaving for patients who are critically ill with COVID-19. For patients on ventilators, the treatment was shown to reduce mortality by about one third, and for patients requiring only oxygen, mortality was cut by about one fifth, according to preliminary findings shared with WHO.
The benefit was only seen in patients seriously ill with COVID-19, and was not observed in patients with milder disease.
Dexamethasone has been found to be useful in serious COVID-19 patients who required oxygen therapy or ICU care. In such patients Dexamethasone reduced mortality by one third. This result was obtained in RECOVERY trial .
https://rebelem.com/the-recovery-trial-dexamethasone-for-covid-19/
Dexamethasone is a life saving medicine no doubt in CCU pateints of Covid19 but there are so many side effects .https://www.medicinenet.com/dexamethasone-decadron-dexpak/article.htm