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Questions related from Harmanjit Singh
Both HCQ and Azithromycin are known cardiotoxic drugs. Provided that COVID-19 infection also leads to myocardial injury and may present with variety of cardiovascular conditions. Will this...
16 July 2020 5,224 8 View
Chemically modified tetracyclines (CMTs) are non antibiotic derivatives of tetracycline having very potent immunomodulatory effects. They inhibit pro-inflammatory cytokine and mediators well...
16 July 2020 6,926 0 View
Minocycline is also a cheaper and older drug with broad spectrum antimicrobial profile. It can offer some advantages over azithromycin which is being combined with HCQS in COVID-19 patients: It...
11 June 2020 5,855 6 View
These revised guidelines have now recommended the prophylactic use of HCQ for all asymptomatic healthcare providers (HCP) involved in containment and treatment of COVID19 and asymptomatic...
26 May 2020 9,753 26 View
IL-6 (considered as prime culprit) and other cytokines (TNF-alpha, IFN-gamma, IL-1, IL-2 etc) are associated with COVID-19 related cytokine storm and further morbidity and mortality . The current...
16 May 2020 3,635 8 View
They have selected drugs for which many studies are already available and most of the studies have shown discouraging results. They have mentioned that they are selecting these drugs based on...
13 May 2020 2,496 7 View
Considering the difficulties linked with obtaining donors, availability of adequate titres of neutralizing antibibodies from each donor and controversial results of the available studies, does it...
06 May 2020 1,923 11 View
BCG vaccine is being seen as a new hope for COVID-19 patients. It can make our immune system to recognize and respond to a variety of infections, including viruses, bacteria and parasites etc...
28 April 2020 7,960 30 View
This is a very controversial issue. Patients who are likely to be prescribed off-label unproven drugs for COVID-19 management e.g. HCQS and Azithromycin , may also develop serious adverse effects...
21 April 2020 2,478 19 View
There is no comprehensive evidence for use of HCQ for prophylaxis of COVID-19. Few studies with small sample and that too with flaws in research methodology are available. Most of the published...
15 April 2020 7,416 21 View
I want to know about biomedical journals publishing undergraduate research articles.
03 February 2020 5,656 3 View
Bempedoic acid inhibits ATP citrate lyase (ACL), an enzyme which converts Citrate to Acetyl CoA . After this step, the pathway is same i.e. Acetyl CoA to HMG CoA and mevalonate (targeted by...
23 January 2020 9,857 3 View
There are few studies in literature where adiponectin levels are measured and compared among patients and controls or pre and post some drug therapy, however, a reference range is not given.
16 January 2020 3,713 4 View
Both PCSK9 inhibitors ans Statins are very powerful LDL-C lowering drugs. To start with, the JUPITER trial reported a 25% increase in NOD with rosuvastatin 20 mg, over a median follow-up of 1.9...
11 October 2019 1,952 1 View
