A recently published extension of SILAC, NeuCode SILAC, requires that data be collected at 480,000 resolution (or minimum 240,000 resolution) for quantification of the 36 mDa spaced precursor masses. I don't have access to anything with greater than about 100,000 resolution. I called MSBioworks and they said the best they have is the Q-Exactive with 120,000 resolution. Is anyone aware of a University of California core lab or commercial service that offers high resolution data collection to enable the use of NeuCode?
What are you looking for es LC-FTMS. Tray with:
http://pendientedemigracion.ucm.es/info/espmasas/Instrumentacion.htm
Traditional FT is too slow for my experiment. I need one of the new hybrid orbitraps - either the Orbitrap Elite or the Orbitrap Fusion.
If you can send your samples to NYC, Columbia has the fusion and MSKCC has an Elite.
http://www.mskcc.org/research/microchemistry-proteomics
http://www.hiccc.columbia.edu/research/sharedresources/proteomics
I know MSKCC's Elite has ETD. Not sure about Columbia's Fusion. You can email Emily Chen and ask.
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