Dear Bhuvana,

Please go through the following link for downloading free-trial of the software:

https://www.scm.com/free-trial/

It is not a free software, you can find more information here:

http://www.cosmologic.de/

You could also try the COSMO-RS module in  the ADF Modeling Suite (COSMO-RS and COSMO-SAC):

https://www.scm.com/product/cosmo-rs/

And in India Tamal Banerjee (IIT Guwahati) also has developed his own COSMO-RS version. 

I wish to predict solubility of astaxanthin in mixtures of acetone and DMSO using UNIFAC software. How can i identify the functional groups of astaxanthin. Structure of astaxanthin can be found in following link-- https://en.wikipedia.org/wiki/Astaxanthin

Following

@Kuldeep: I think a decent UNIFAC implementation should recognize those functional groups if you insert a SMILES string (which you can also find on the Wiki page?

Dear Bhuvana,

Please go through the following link for downloading free-trial of the software:

https://www.scm.com/free-trial/

T. P M Goumans Thank you very much Sir. I have calculated the solubility of astaxanthin in mixtures of acetone and DMSO using UNIFAC software. Your suggestion was very fruitful in quantification of fundamental groups and calculation as well. Thanks a lot.

Are there some comercial software with an implementation of COSMO-RS-PDHS? Is SCM the best option?

Hi we don't have PDHS (yet) but there could be other efficient ways to deal with electrolytes. Feel free to reach out to us.