To evaluate the release kinetics of micro and nanosuspensions containing small molecules, what optimum conditions must be defined?
Ratio between MW of the small molecule vs pore size of the membrane (1:10, 1:100)?
Ratio between volume of dialyzed material 1:10, for example?
What are the main reasons for absence of permeation?
Gilles Dollo
Dear Mafalda,
you can find some responses in this paper
Drug Deliv Transl Res. 2013 October 1; 3(5): 409–415.
doi:10.1007/s13346-013-0129-z
Hope this helps.
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