Hello Fa Ro
Yes. The spleen plays an important role in the immune system. It produces lymphocytes and is important for T cell maturation. It acts as a filter for blood as part of the immune system. Old red blood cells are recycled in the spleen, and platelets and white blood cells are stored there. Different parts of the spleen specialize in different kinds of immune cells.
The spleen contains a sizable population of natural killer T (NKT) cells and are involved in a broad range of immune responses by secreting cytokines and inducing downstream activation of adaptive immune cell types.
I hope this is helpful.
Best Wishes.
Hi, Fa Ro
very large
Only a small amount of peripheral blood can be collected from mice, and it is difficult to obtain a large number of mature lymphocytes.
The spleen contains a large number of mature lymphocytes.
Best,
Hello, Fa Ro!
Please You also look at the article:
Article Structure and function of the immune system in the spleen
THE CELLULAR INITIATORS AND EFFECTORS OF THE ADAPTIVE SPLENIC IMMUNE RESPONSE
In this section, cellular functions and organization specific to the spleen will be discussed. Most of the work identifying cell subsets, location, and function has been performed in mice, and how these compare to humans remains to be clarified.
Fig. 2 The cellular organization of the murine WP is dynamic.
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