🔬 In our recent study titled “Effect of 1% Phenytoin Muco-Adhesive Paste on Improvement of Periodontal Status in Patients with Chronic Periodontitis,” we explored an unconventional therapeutic approach. Rather than its traditional role in neurology, Phenytoin was reformulated into a muco-adhesive paste for targeted application on inflamed gum tissue.

What emerged was a new perspective on an old drug:

🔸 It stimulated fibroblast activity

🔸 Promoted granulation tissue development

🔸 Helped reduce inflammation

This led to gradual healing in chronic periodontal lesions—where physiological distress met a biologically empathetic response.

📌 The findings prompt a deeper question: can systemically known medications be repurposed for localized, patient-friendly therapies?

📊 We’d love to hear your thoughts on formulating adjunct treatments and navigating unconventional therapeutic paths.