We developped a webtool to easily analyze all sort of screening results, using all usual metrics in the field. You can generate ROC curves and more very quickly from your browser, see http://stats.drugdesign.fr.
Webtool associated publication : Screening Explorer – An Interactive Tool for the Analysis of Screening Results (http://pubs.acs.org/doi/abs/10.1021/acs.jcim.6b00283)