What would be a good positive control for measuring hepatotoxicity?

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Ali Asghar Moshtaghie

measuring galutamyl transferasemma g

Amira M Gamal-Eldeen

This is a list of hepatotoxic agents (with IC50) with different hepatic cell lines.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277728/table/T3/

Ron Scialis

Wouter,

In addition to GGT (Ali's response), measuring alanine aminotransferase (ALT) is also a good indicator of hepatocellular damage. Acetaminophen is a good agent that can reliably induce hepatic injury.

Ron

Professor Dr. Naser A Al-Wabel

For acute induction of hepatitis, carbon tetra chloride is very powerful but none reversible

Wouter Feitz

Thank you all for your responses!