Cyclohexane 1,2,3-triol is a triol, which means it has three hydroxyl (-OH) groups on its cyclohexane ring. Tosyl chloride (TsCl) is a reagent that can convert hydroxyl (-OH) groups into tosylate (-OTs) groups. EtONa is a base that can help deprotonate the hydroxyl groups.
Therefore, when cyclohexane 1,2,3-triol reacts with tosyl chloride and base EtONa, the hydroxyl groups on the triol will be converted into tosylate groups. The reaction will likely proceed as follows:
EtONa deprotonates the hydroxyl groups on the triol, forming cyclohexane 1,2,3-triolate anions.
Tosyl chloride reacts with the cyclohexane 1,2,3-triolate anions, replacing the -OH groups with -OTs groups. This reaction is an example of nucleophilic substitution, in which the tosylate group acts as a leaving group and is replaced by the cyclohexane 1,2,3-triolate anion.
The overall reaction can be represented as:
Cyclohexane 1,2,3-triol + TsCl + EtONa → Cyclohexane 1,2,3-triolates with tosylate groups
The resulting product will be a mixture of cyclohexane 1,2,3-triolates with tosylate groups. This reaction can be useful for protecting the hydroxyl groups in the triol, which can be deprotected later if needed.