It is found that vitamin C supplement helps in reducing MDA level in liver disease patient. Further studies suggest that zinc level is reduced in liver patient. So what will be the relation between MDA and Zinc?
Again we know that NO is a lipid peroxidation products. If NO (Nitric oxide) is also increase in liver patient then what will be the relation between zinc and NO?
Dear Uddin,
The Zinc “participates in antioxidant defence by inhibiting NADPH oxidase, acting as a structural and catalytic component of the enzyme superoxide dismutase and inducing the synthesis of metallothionein” (http://www.sciencedirect.com/science/article/pii/S0301054613001134).
For you to understand what is MDA, follow a link: http://www.hindawi.com/journals/omcl/2014/360438/
NO is not a product of lipid peroxidation. For you to understand what is NO read the article entitled: "Nitric oxide production and signaling in inflammation". Curr Drug Targets Inflamm Allergy. 2005 Aug;4(4):471-9.
I hope have helped.
Best regards,
Kívia
Dear friend, tgere are several literatures in this area especially regarding to vitamin c, zinc etc with lipid peroxidation, with a little research in google scholar you will find valid articles in laboratory animals, sheep, and the others. Recently we published two articles which you will kindly find some valid sentences regarding lipidperoxidation on them.
Regards,
Mehdi
It will be more helpful if you give the link of your suggested info.
Thanks
Foloow other link about Zn: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429650/
Best regards,
Kívia