I can´t manage to dissolve a solid Nitrogen-containing heterocycle-Polyoxometalate hybrid material to perform a liquid 31P nmr. I´ve tried:
Solvent relative polarity
CHCl3 0,259
(CHCl3/DMSO)
DMSO 0,444
CH3CN 0,460
H2O 1,00
THF 0,207
Hexane 0,009
C.Hexane 0,006
CCl4 0,052
C2Cl4
DMSO slightly dissolve it ( but it leaves some small particles in suspension), my questions is: How can I approach the analysis of this dissolution apart from its polarity ? since those solvents have a quite interesting range of polarity and do not work.
P.S. I can´t use a strong acid or base since the hybrid decomposes in other species. I am also aware of Solid NMR.
There is another parameter other than polarity which is selectivity. I have seen this effect in chromatography.
I had 2 chemical compounds that had the exact same affinity for ethyl acetate/hexanes mixture no matter how I changed the proportions.
It wasnt until I switched out ethyl acetate for dichloromethane that I saw the two compounds separate. It wasnt polarity that separated the two, as altering the ethyl Acetate proportion wouldve caused them to separate, it was selectivity.
That being said, if DMSO slightly dissolved compound maybe try other solvents such as HMPA or DMF.
My suggestion would be CD3OD and its mixtures: CDCl3/CD3OD or perhaps DMSO-d6/CD3OD. I noticed that for some substances solubility in CHCl3/MeOH is often much better than in pure CHCl3 or MeOH.
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