...that can be detected via Western Blots in cardyomyocites, besides CD71 (transferrin receptor), CD147 (EMMPRIN) and CD29 (Integrin beta1).
Dear Dmitry,
The attached publication includes most of the proteins that are reliable markers of non-lipid raft membranes:
Arch Immunol Ther Exp, 2004, 52, 215–224
PL ISSN 0004-069X
Role of lipid rafts in T cells
Sunil Thomas, Rajeev Kumar S. and Teodor−D. Brumeanu
Summary
The plasma membrane of T cells is made up of a combination of phospholipids and proteins organized as glycolipoprotein microdomains termed lipid rafts. The structural assembly of lipid rafts was investigated by various physical and biochemical assays. Depending on the differentiation status of T cells, the lipid rafts seclude various protein receptors instrumental for the early T cell signaling, cytoskeleton reorganization, protein and membrane trafficking, and the entry of infectious organisms into the cells. This review article summarizes recent information on the assembly of lipid rafts in plasma membrane of T cells and their signaling output in mature and thymic precursors towards cell growth and differentiation, and possible modalities by which the function of lipid rafts
can be altered by drugs and T cell ligands. The concept of using lipid rafts as a target for pharmaceutical compounds and biological T cell ligands to ultimately alter the T cell function is discussed
Among the proteins discussed: the cytoplasmic Syk-family kinase ZAP-70 and CD28 and CTLA-4.
Hoping this will be helpful,
Rafik
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