After the dsDNA nucleic acid enter the nucleus of the host cell it is transcribed from host DdRp II to form 2 strands of mRNA complementary to the 2 DNA strands of the virus nucleic acid.
Does this process produce 2 complementary strands of mRNA that should match each other?
After the transcription each mRNA strand leaves the nucleus, but why those will not match to form a dsRNA and will not trigger the PTGS?
Adam B Shapiro
Only one of the DNA strands is transcribed into mRNA, so there is no possibility of complementary mRNAs base pairing.
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Emilio Gasparini
Thank you for the answer, I confused the 35S and 19S RNAs with the transcription product of both strands of dsDNA; they comes from the transcription of the same strand instead.
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