Hello,
what methods can I use to effectively test the antidiabetic properties of plant extracts? α-glucosidase inhibition, α-amylase inhibition, or maybe something else? Maybe you have proven methods? I would be grateful for any suggestions.
Sundar Rajan
Two methods one is invitro next one invivo, invitro method using α-glucosidase inhibition and α-amylase method in addition hepatic cell line study useful for the optimized the activity
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Shehu Usman Abdullahi
In vitro= Inhibition of carbohydrate hydrolysing enzymes Assay. Inhibition of DPP4, SGLT 1 & 2 etc. Furthermore, the use of cell lines to ascertain the effect of extract on glocuse absorption
In vivo= Using experimental animals such as rats, mice and even Drosophila melanogaster.
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