I have a group of subjects with XX disease enrolled in 2013-2016. After standard assessment, Patient received surgery or conservative treatment in terms of their own willing.
Recently I performed a telephone interview to inquiry their current functional outcome at the same time point.
My research question is:
1). Which treatment is more effective?
2). Is admission of year a predictor for functional outcome in terms of different treatment? (e.g. For surgery, is functional outcome going better as time goes by whereas for conservative treatment, is functional outcome going worse as time goes?)
3). For those patients who received conservative treatment, what factors may affect their functional outcomes?
Based on these questions, what may be your analytical method to deal with?
Thanks.
Dear Deng
You may feed your data on a statistical package like SPSS for example. for each patient in the two comparative group you enter the data related to various variables you studied including sociodemographic, clinical, treatment and outcome indicators describing their status at the time of re-contact. Then the analysis of data is made using cross-tabulations and Chi-Squared and other statistical tests. Remember that your study is not a perfect clinical trial> it is better to be analysed as cohort study
1. difference between conservative and surgery at time x. Compare mean functional score
2. time trend. Compare slopes of regression of functional score on time between conservative and surgical group.
3.other variables in conservative group at time x. Do multiple regression of functional score on other variables, quantified ,binary or ordinal.
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