What make colistin toxic to kidney and nervous system?

Chooseel Bunsuwansakul @Chooseel_Bunsuwansakul

03 March 2018 1 3K Report

thank you in advance

chooseel

Is the peptide a polyarginin or polylysin? In other words does it have charge? if it does, you can read these papers on crotamine and protamine, that proppose a physical chemical interpretation for the peptides effect.

DOI:10.2174/092986732112140319102212

DOI:10.1016/j.bbagen.2013.10.031

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