Dear All,
May be it is a silly question. I need to functionalize a glass surface for binding some parasite specific lipids and proteins. What kind of functionalizing agents could be used for the same purpose apart from antibodies. Can anyone help me here. Thanks in advance
There are number of glass functionalizing agents, call site coping agents that can work. It depends on the specific protein or lipid. See the following on p27: https://www.gelest.com/themencode-pdf-viewer/?file=https://www.gelest.com/wp-content/uploads/Goods-PDF-brochures-couplingagents.pdf
and https://www.gelest.com/themencode-pdf-viewer/?file=https://www.gelest.com/wp-content/uploads/Whole_cell_and_cell_organelle_immobilization_on_siliceous_substrates.pdf
@Barry Arkles Thank you so much for your suggestion. Really appreciated. I have a question to ask. Are glutetaldehyde/APTES only binds with lipids/proteins or with whole cell?
Dear Thulya Chakkumpulakkal Puthan Veettil
Protein/aptamer/antibody can be bind onto the -COOH, -NH2, -CHO, thiols group functionalized surface.
For further information you can follow this articles
1. Article A Polyallylamine Anchored Amine-Rich Laser-Ablated Graphene ...
2. Article Trimetallic Pd@Au@Pt nanocomposites platform on -COOH termin...
3. https://iopscience.iop.org/article/10.1149/2.0361912jes/meta
Thank you
- Badges
- Science topic
- Similar topics
- Physical Sciences
- Materials Science
- Materials
- Inorganic Materials
- Ceramics
- Glass