Will it be possible to get IC:50 if we target cancer cell line with antibody drug conjugate (ADC) that have 50% less antigen positive cells ?

Is it possible to attain IC50 if my target cells have less than 50% antigen expression ? For example: Cancer cell line XXX is showing 35% of expression of cell surface antigen YYYY, if i...

04 February 2021 2,711 3 View

How to give noncollinear magnetism terms in INCAR for Double helical magnetic ordering in VASP?

Usually, the magnetic moments of noncollinear tags in the INCAR file look like MAGMOM = 0.0 1.0 0.0 if the atom has 1 unit of the magnetic moment along the b axis. But if we consider the magnetic...

19 November 2020 8,061 3 View

What will be the impact on Socio-Economic activities of man after the end of COVID-19 Pandemic?

I am very much thankful of the experts, researcher, and thinkers for very thought full discussion on my previous question on Role of Geography on COVID-19 Pandemic. Now I am keeping another very...

19 October 2020 6,552 4 View

Can someone let me know the best SiRNA along with negative controls for silencing NEAT1 in human breast cancer cells. Company and price if possible?

SiRNA for NEAT1 knockdown in breast cancer cells

05 October 2020 9,723 1 View

I would like some guidance for my project on RECLAMATION OF CONSTRUCTION MATERIALS FROM INDUSTRIAL SLUDGE?

I request the professionals in this to please help me in my project which i am doing in my final year. I'd be very grateful even if its just a bunch of research papers or websites that your...

27 August 2020 3,863 2 View

I am keeping the Question for discussion, What is the role of Geography in the study of COVID-1 pandamic?

Please give your opinion and suggestions

10 August 2020 3,990 19 View

Number of cores and nodes on running vasp on HPC?

I wanted to know how do you determine how many cores and noes you will need to perform an DFT analysis for particular molecules?? I normally use two cores for all my calculations and it pretty...

30 July 2020 4,279 5 View

How the INCAR file is different for SCAN and PBE+U for VASP?

Hi, I am trying to run a SCAN functional calculation in vasp. I have run the DFT for GGA+U in VASP before. So I was wondering what I need to deduct and add to my GGA+ U INCAR file to prepare it...

11 July 2020 334 3 View

What is the likely impact of AI on future jobs across all sectors?

We have been witnessing the advent of AI and its rapid proliferation as an intelligent machine in many applications from driverless cars, and much more. How is the lifestyle going to change as a...

05 May 2020 4,787 41 View

What is the inference from the delocalization of P-orbital?

I have attached an image. Can you kindly explain what does it mean from the delocalization of P-orbital from the LUMO plot? I have made a statement " From the LUMO plot it is seen that the...

30 March 2020 9,796 3 View

Does anyone know an alternative product for cardiac Troponin T antibody for Immunofluorescence (Thermo # MA512960)?

We have been using Thermo Fisher anti-cardiac Troponin T antibody for immunofluorescence staining in FFPE mouse heart sections but it was recently discontinued. The literature shows it to be the...

01 March 2021 4,937 1 View

Is there a deep reason for using the squared modulus of the wave function as the probability density of the existence of the particle?

I think we were all surprised at the first time we got to know quantum mechanics that the squared modulus of the wave function is the probability density of the existence of the particle? The role...

28 February 2021 6,282 9 View

How to perform EEG classification of Alzheimer and control groups?

I am doing a project on classification of EEG signals of Alzheimer's disease and control groups. Previously, I extracted the alpha power of the EEG signals and found out the strengths. I want a...

18 February 2021 8,502 2 View

Despite single-cell RNA, how can I characterize a new cell subtype/phenotype?

A new cell subtype was found out only during regeneration phases after a cuprizone-induced demyelination model. How can I characterize this cell? It is important to highlight that was already...

13 February 2021 1,245 1 View

Hello .Ineed a researchs about systolic heart failure any one can help me ?

Am a master student .I need an information about this case to write my thesis?

09 February 2021 9,706 2 View

Does anyone have a stack of images of action potentials or abnormal brain scans?

I need a stack of black and white .jpeg/.tiff/.jpg/.png images across time of either action potentials, neurons firing, or brain scans (comparing disease and normal brain, disease progression,...

09 February 2021 2,648 3 View

Applications of General Multiple Sums?

Does anyone know of applications of multiple sums of a sequence? I know of the Multiple Zeta values (which is a multiple sum of 1/N^s). This has multiple applications in quantum physics, QED,...

08 February 2021 8,047 12 View

Does diseases like fungal,bacterial etc of rice plant is different from nutrient deficiency diseases?how deep learning is used except classification?

can any one suggest me other than classification, how deep learning technique can be used in plant disease detection in rice plant? could a research work continued from fungal,bacterial...

07 February 2021 470 2 View

How can I select the best plasmid after sequencing?

I have transformed a drought-related gene of 1.7kb into pGEMt vector (E.coli DH5 alpha strain). After sequencing the plasmids (3 replicates) 4 changed amino acids are visible at different...

06 February 2021 336 3 View

Patients with chronic kidney disease could get COVID-19 vaccine?

04 February 2021 278 4 View