Researchers hope to use embryonic stem cells, which have the unique ability to generate virtually all types of cells in an organism, to grow healthy tissues in the laboratory that can be used replace injured or diseased tissues. In addition, it may be possible to learn more about the molecular causes of disease by studying embryonic stem cell lines from cloned embryos derived from the cells of animals or humans with different diseases. Finally, differentiated tissues derived from ES cells are excellent tools to test new therapeutic drugs....any information about it
Hi, Neeran.
Cloning involves recovery of unfertilized oocytes, obtaining somatic cells and final somatic cell nuclear transplantation into the enucleated oocyte prior to oocyte activation to allow early embryonic development in vitro up to blastocyst. However, unlike animals, human cloning is prohibited in most countries. Thus, cloned human embryos cannot be transferred to the uterus to allow further development under the law in every country. However, under a strict regulation, human embryo cloning up to blastocyst is possible to establish human embryonic stem (hES) cells from the cloned patient-specific ES cells. This cloning is called therapeutic cloning for the research and development of therapeutic measures to treat the patient. Patients suffering from incurable diseases would donate somatic cells as a somatic cell donor. If we could get oocyte donation from women who should undergo superovulation, oocyte recovery from each growing follicles of both left and right ovaries before ovulation, and in vitro maturation, followed by freezing until use. Many women would suffer from the hormonal hyper-stimulation and surgical procedures. Despite the ethical, legal, social issues, some of supporters for therapeutic cloning would save life in the future by providing different disease types of hES cells for drug screening, drug testing, and development of therapeutic ways, and tools for people suffering from rare diseases. The concept of iPS cells have recently replaced the idea of therapeutic cloning. However, at the moment, hES and iPS cells seem to lose their grounds for therapeutic purposes for replacing damaged body parts due to possible adverse effects to be studied probably for many decades.
Regards.
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