Liver damage due to ingestion of alcohol is a well known phenomenon in animals. It is well-established that ethanol inhibits the mitochondrial electron transport chain, resulting in increased ROS production . So the oxidative stress plays an important role in the development of alcohol liver disease.

There are two types of fatty liver diseases

1. Non-Alcoholic Fatty Liver Disease (NAFLD): Caused as a consequences of metabolic diseases such as high cholesterol or triglycerides and diabetes or prediabetes (insulin resistance). Other potential causes of NAFLD include: medications, viral hepatitis, autoimmune or inherited liver disease, rapid weight loss and malnutrition. The symptoms of NAFLD include fatigue, weight loss or loss of appetite, weakness, nausea, confusion, impaired judgment, or trouble concentrating. Over time, subjects might have pain in the center or right upper part of the abdomen , an enlarged liver, patchy, dark skin discoloration, usually on the neck or underarm area.

The other severe type of FLD which is called

2. Alcoholic Fatty Liver Disease (AFLD): symptoms may worsen after periods of heavy drinking. The disease process can stop or reverse, or it may worsen. If cirrhosis develops, the liver loses its ability to function. This can cause signs and symptoms such as: Fluid retention, Muscle wasting, Internal bleeding, Jaundice (yellowing of skin and eyes), and Liver failure. Subjects suffering from NAFLD if drinks alcohol regular and uncontrolled manner make the situation beyond manageable with irreversible liver damage and cirrhosis.

Thus to make the long story short liver damage and cirrhosis are the most important damage associated with FLD.