Hi,

I have a protein target with unknown 3D structure. I'm trying to use comparative modelling in order to predict it's structure.

For the identification of Homologous proteins I would like to use different similarity searching programs (Blastp, HHpred, HHblits...) and compare the results.

For I-TASSER I would like to know what is the similarity searching algorithm that it uses and its principle?

Thank you in advance for your help.

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