What is the role of N-Nitrosobis(2-oxopropyl)amine reagent in amide formation?

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Adel Amer

Nagapradeep

I see your point and it might be a mistake. Benzotriazole-1-yloxy- tris-(dimethylamino)-phosphonium hexafluorophosphate (BOP; Castro’s reagent) is well known for the coupling of amines with carboxylates and has the same abbreviation BOP !

Good luck

Nagapradeep N.

Dear Dr. Amer,

Thanks for your insight.

But, Please see the following reference as well. The same reagent is used in the similar context of making amide (highlighted in yellow). I think it may not be a mistake. I just want to know, what is its role in making amide?