Silver nano-particles are known to provide antimicrobial properties in medical textiles. They can be incorporated into medical textiles in two ways. By having them introduced into the polymer during the yarn production itself OR after the textile fabrication , ie. loaded as entrapped particles during the yarn bundling, weaving or knitting process. Which one of them is a preferred practice from the manufacturing as well as efficacy point of view?
I would suggest post-treatment of fibres. In case of applying Ag-NPs during spinning release of Ag-ions can be at least reduced. I would suggest a combined wet-chemical treatment of the textile, e.g. post treatment with polymers being able to bind silver and silver nitrate followed by photochemical reduction of Ag-ions to Ag-NPs. We usually apply an aqueous solution of polyethyleneimine and AgNO3 to the textile surface and then irradiate in UV. Advantage of this in situ formation of Ag-NPs is that you will be able to avoid any problem with aggregation of NPs.
Dr. Helga Thoams, Thank you for your suggestions.
Have you ever noticed the release of Ag-NPs into the blood stream, especially for blood contacting applications, which could lead to aggregation of Ag particles and eventually result in micro-thrombus formation?
Dear Dr. Muraleedharan C Vayalappil,
Our work is concentrated on antimicrobial textile treatments for uses in clothing and technical applications, not for applications in direct contact with blood.
Therefore I'm not being able to answer. However, the question is very interesting. In case you have some indications, please, let me know. I'm always super currious.
Best regards.
Helga
Dear Dr Muraleedharan,
Colloidal silver is not approved by FDA for internal and external application.
Majumdar
Depends on the purpose of the textile
i for antimicrobial treatment of the fabric/skin surface generally (minimise odour, preserve fabric itself, OR
2 for treatment of a wound (i.e. release to the site of injury/wound).
Primarily to prevent / minimize implant related infections
it might be fruitfil for burn dressings with silver nanoparticles . this approach will not only provide protection against burn but also enhance the efficacy of silver also.
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