Dear Author

Please read the following paper published in Br J Pharmacol, you will get your answer

Jacques Damas, Claude Hallet, and Pierre J Lefebvre. Changes in blood glucose and plasma insulin levels induced by bradykinin in anaesthetized rats. Br J Pharmacol. 2001 November; 134(6): 1312–1318.

All the best

Dear Author

Please read the following paper published in Br J Pharmacol, you will get your answer

Jacques Damas, Claude Hallet, and Pierre J Lefebvre. Changes in blood glucose and plasma insulin levels induced by bradykinin in anaesthetized rats. Br J Pharmacol. 2001 November; 134(6): 1312–1318.

All the best

Respected Dr. Meo,

Thank you vary much for your reply, I read this paper in past and the data related to insulin is not shown in the paper (pg. no. 1315, left column bottom second line.) give the detail of level in normal and in STZ treated rat at different time.

Sincerely yours

Please see these papers and attached:

Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by insulin. Havel PJ, Uriu-Hare JY, Liu T, Stanhope KL, Stern JS, Keen CL, Ahrén B.

Am J Physiol. 1998 May;274(5 Pt 2):R1482-91. PMID: 9612417 [PubMed - indexed for MEDLINE]

Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats. Havel PJ, Hahn TM, Sindelar DK, Baskin DG, Dallman MF, Weigle DS, Schwartz MW. Diabetes. 2000 Feb;49(2):244-52. PMID: 10868941 [PubMed - indexed for MEDLINE]

The other STZ Rat Paper: