'What is the most reliable database or source for cancer known/approved drugs' target?

More Abdullateef Nashed's questions See All

Is there a method or a published work on the comparison of a basal phenotype between two cell lines ?

I wonder if it is possible, in concept, to evaluate the basal phenotype of cell lines, and compare them. For example, If you want to compare the apoptosis potency of cell line A to that of cell...

12 November 2018 371 3 View

CPLEX with C VS. Matlab?

Dear all Kindly if you have experience with CPLEX solver with C, Is it better to model the optimization problem using C or C++ than Matlab, from execution time point of view? In fact I have...

26 July 2018 9,078 2 View

BP Reaction in gateway system is not working, any suggestions?

Helloi am trying to construct an entry clone using gateway system. i designed the attb1,attb2 adopters to my primers and checked the purity of PCR product on gel. everything seems to be good. i am...

24 February 2016 8,610 4 View

How can I localize a protein, detected by 2D immunoblotting, on the silver staining gel?

I have been struggling in trying to localize the protein of interest i detect by 2D immunoblotting on duplicated silver staining.i tried to duplicate the 2 D gel and use one for 2D Immunoblotting...

08 June 2015 2,062 3 View

Any suggestion on organic extraction of indole's derivatives from aqueous solution ?

i am growing a bacteria in TB medium and i suspect presence of one coloured compound to be an indole's derivative. is there any recommended method to extract this compound in order to obtain...

08 March 2015 4,467 1 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

How to empty large intestine in mice ?

Hi all I am working on colon-targeted drug delivery for which I kept mice fasting for 6h using fasting grills during scotophase (dark period). I observed liquid fecal content in the cecum and...

23 February 2021 7,701 2 View

Can I use a protein-devoid condition as my negative control in ELISA?

Hello, I am running a sandwich-type ELISA where I am trying to inhibit a protein-protein interaction using small molecules. For each experiment, I determine my Z' (Z-prime) to determine the...

23 February 2021 7,429 1 View

How does the injection volume impact LLOQ and ULOQ in regression analysis (LC-MSMS)?

Hello, I have run into an issue that has sparkled a debate at work: is the LLOQ/ULOQ impacted by injection volume under the following circumstances: 1) Same dilution factor of all samples 2)...

23 February 2021 9,159 3 View

Can two EC50 values with different hill slopes be compared?

Hello, I fit a classical dose response curve Y=Bottom + (Top-Bottom)/(1+10^((LogEC-X)*HillSlope)) to my data (not related to inhibitors etc). The model I use is purely qualitative but it fits...

23 February 2021 8,155 5 View

Found that there was a multiple band when amplifiying targeted gene ?

i few days ago amplified specific gene using PCR with specific primers, but there was a multiple band in electrophoregram i found. out of 10 sample amplified, there was multiple band and there was...

18 February 2021 5,131 5 View

How can I import .sav file into LISREL?

I've just downloaded free trial version of LISREL 10.3 but I got stuck with importing .sav (IBM SPSS 25.) file. I mainly followed the steps of this video...

15 February 2021 752 2 View

Which alginate is best for making gel for wound dressing application?

We are looking into utilizing alginate as a gel coating on an HDPE substrate for drug delivery. I would like to ask the community about their experience with alginate and which commercial sources...

15 February 2021 4,319 4 View

Any natural extract (that is easily available) or any drug combination triple which i can use against gram negative?

I'm working on gram negative i want to use any natural extract (plant extract) or triple drug combination against its biofilm formation.

14 February 2021 1,403 3 View

Should the AUC in a concentration-time graph of a subcutaneous implant be roughly the same for poeple?

I have 2 concentration time curves of a subcut drug implant. the first group has a peak around the 50 day mark where as the second group does not. Both groups received the same implant by the same...

10 February 2021 2,305 3 View

Rakesh Kumar Tekade

Hi ABdullateef,

Please refer link below:

https://www.centerwatch.com/drug-information/fda-approved-drugs/therapeutic-area/12/oncology

Gaurav Joshi

Please Follow the given links:

http://crdd.osdd.net/raghava/cancerdr/

https://www.cancer.gov/about-cancer/treatment/drugs

https://www.cancer.gov/publications/dictionaries/cancer-drug