What is the molecular mechanism behind the treatment of Myasthenia gravis with Acetylcholinesterase inbibitor?

26 September 2019 1 2K Report

Myasthenia gravis is an autoimmune disease, that affect the cholinergic receptor and also in some variant muscle specific kinase. More Acetylcholine against reduced and unavailable receptor......? A ligand binds by availability of receptors?

Enrique Soto

Your guess is correct: more Ach to a scarce receptor, and yes increasing ligand concentration increses the rate of ligand-receptor binding according to law of mass action.

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