What is the method to calculate the percentage of MIC and MBC value of a drug?

01 April 2022 0 5K Report

I have worked on the minimum inhibitory concentartion of ciprofloxacin. Can anyone guide me the method to convert MIC value into a percentage?.

Badges
Science topic

More Kiran Aziz's questions See All

What is the suitable solvent of MIL-100 for chemotherapy?

I synthesised a nanocarrier by conjugation MOF (MIL-100) with folic acid for use in chemotherapy but the samples didn't dissolve completely in aqueous solution or DMSO. Instead, they only...

19 July 2024 8,522 0 View

What is the suitable solvent of MIL-100 for chemotherapy?

I synthesised a nanocarrier by conjugation MOF (MIL-100) with folic acid for use in chemotherapy but the samples didn't dissolve completely in aqueous solution or DMSO. Instead, they only...

15 July 2024 2,414 1 View

How can we create an AI system that autonomously develops entirely new scientific theories without any human input or predefined knowledge base?

Wikipedia on AI in Scientific Discovery: Artificial intelligence (AI) has shown significant potential in scientific discovery, helping to accelerate research processes and uncover new insights. AI...

25 June 2024 8,311 3 View

What is Academic Research Paper?

I do a research about Non-Verbal Communication: Gestures and Body Language in Classroom.

18 June 2024 8,737 1 View

How should I interpret this moderation analysis (PROCESS Macro)?

Hi there! I was wondering how I should go about interpreting the following data. I am currently investigating the moderating role of working memory (continuous) on the relationship between...

07 June 2024 1,473 0 View

Is there any chance that the Agros Gel crack by itself?

Yesterday, my Agros gel broke by itself (unknown reason). I was busy & gel remained on the caster for at least one hour.

04 June 2024 5,063 0 View

After the addition of nuclease-free water in DNA samples, After how long we can run gel electrophoresis ?

The question asks about the timeframe for running gel electrophoresis after nuclease-free water has been added to DNA samples.

03 June 2024 1,639 3 View

In which solvent can silver, zinc oxide and silicon dioxide nanoparticles be dissolved?

I am trying to find the appropriate solvent to dissolve these nanoparticles for the antimicrobial test. And how will I do an antimicrobial test if these nanoparticles do not dissolve?

14 May 2024 401 6 View

Which regression analysis will be applied if there are 7 nominal dependent variables and 1 ordinal independent variable?

which regression analysis will be applied if there are 7 nominal dependent variables(YES/NO categories) and 1 ordinal independent variable(3 categories: Low, normal, high)?

23 April 2024 9,971 3 View

Does a expired loading buffer degraded the protein in Westron blot? or changed the shape of protein band?

My western blot had a problem with the protein band. I just checked it and observed my loading buffer is expired. does anyone explain it is due to expired loading buffer or any other problem i...

11 April 2024 4,354 3 View

Is changing the medium during the experiment overestimate the results?

I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...

07 August 2024 2,283 2 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

Can i quantify a nanoparticle encapsulated in cell culture medium by hplc?

Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...

03 August 2024 2,730 1 View

Is it necessary to attach fluorophore at 3' end in MIC RT PCR machine for Dual hybridization Probe designed especially for genotyping assay?

I designed 2 dual hybridization probes for my single SNP. where I attach my fluorophore 5'-FAM-nnnn-BHQ1-3', and 5'-HEX-nnnnnn-BHQ2-3'. I need to run it on the MIC RT PCR machine by Biomolecular...

28 July 2024 5,658 0 View

How to calculate FIC index?

Can someone explain to me how was the MIC of MO in combination and MIC of antibiotic in combination was calculated? as shown in the attached file below.

26 July 2024 2,702 1 View

How to maintain the drug concentration in cell culture study for long term?

I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...

24 July 2024 8,696 0 View

How can I determine if a drug binds to a ribosome using a Cryo-EM map?

Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...

19 July 2024 2,155 0 View

How to calculate percentage cumulative drug release?

How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...

15 July 2024 4,192 1 View

MTT assay - 6 well plate?

Hi, In the 6 well plate, when I am seeding the cells. Do I add 1ml of complete media to one of the wells for the control at this stage or do I wait unit I am treating the plates to do that? Also...

13 July 2024 9,783 1 View

How to convince decision makers to adjust the legislation to allow opening of drug consumption rooms?

In my country, there is a lot of public outcry in relation to the presence of drug injection and related behaviors in public. Hence at least the bigger cities would probably benefit from the...

08 July 2024 8,903 1 View