What is the meaning of binding site size (s) in DNA binding studies?

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Amit Kumar

Dear Dr Ostaff

Thank you very much for your kind help. Here, CT-DNA refers to Calf thymus DNA. The term binding site size has been used to explore the binding interactions between DNA and anti tumor agents. Please suggest me any reference wherein, binding site size has been explained in detail.

Felipe Diógenes Abreu

Amit, you question is also important to me. I would like the exact meaning of binding size. Can I suppose that If the binding size is equal to 1 the drug interaction occur through one base pair?