Parkinson's disease (PD) is a neurodegenerative disorder that affects predominately dopaminergic neurons in a specific area of the brain called substantia nigra. While Parkinson’s itself is not fatal, disease complications can be serious. The Centers for Disease Control and Prevention (CDC) rated complications from PD as the 14th cause of death in the United States.
Currently, all therapies used for PD improve symptoms without slowing or halting the disease progression.
So at present what is the life expectancy of a Parkinson's patient?
Article Estimated life expectancy of Parkinson's patients compared w...
I would be interested if you knew of other newer articles.
We tested physical activity as a treatment for PD. Look if it gives you any idea:
Please take a look at the following RG links.
Article Early predictors of mortality in parkinsonism and Parkinson ...
Article The estimated life expectancy in a community cohort of Parki...
Article Estimated life expectancy of Parkinson's patients compared w...
Please also have a look at the following useful links.
https://www.quora.com/How-long-can-a-person-live-with-Parkinsons-disease
https://www.quora.com/What-is-the-life-expectancy-of-someone-with-Parkinsons-disease
The group of diseases that suffer damage to the central nervous system is the most common Parkinson's disease in the world. One of the risk factors for the disease is aging. This causes anxiety for everyone, especially over 60 years. The basis of the pathological process is the death of nerve cells in the brain, leading to reduced secretion of dopamine, which is necessary for the transmission of pulses. Because of the decrease in dopamine content, the function of cells responsible for locomotor activity and muscle tone in the body is unstable. But the evolution of the disease occurs with the death of at least 70 - 80% of the neurons. Parkinson's disease has a chronic course, and it is completely impossible to cure it. Previously, life expectancy was no more than 7-8 years. But, with timely treatment to help, and pass cycles of modern treatments and surgical treatment, observation in dynamics and adjuvant therapy you can slow disease progression, improve quality and life expectancy to 20 years. For many years, you can maintain the ability to work.
There are many factors that influence life expectancy in patients with PD. These range from genetic factors that influence age at onset to quality of care and history of exposure to chemicals that modify disease onset and progression. Michael J Fox was diagnosed with young onset PD at age 29. He is now 57 years old. So he has lived with the disease for over 25 years!
Four milestones of advanced disease (frequent falls, visual hallucinations, dementia and need for residential care) occurred at a similar time from death in each group. On average, visual hallucinations preceded death by 5.1 years; regular falls by 4.1 years, dementia by 3.3 years, and need for residential care by 3.3 years. Please take a look at following paper: https://academic.oup.com/brain/article/133/6/1755/353024
Takafumi Hasegawa Thank you so much, your interesting contribution was very helpful to me.
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