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Questions related from Francesco Lusciano
Arginine is the substrate for nitric oxide synthesis, which is pivotal to vascular homeostasis and linked to the insulin response, it has long been posited that supplemental arginine could benefit...
17 February 2020 9,555 9 View
The neurovascular plasticity of hippocampus is an important theory underlying major depression. Ketamine as a novel glutamatergic antidepressant drug can induce a rapid antidepressant effect...
13 March 2019 7,692 14 View
Parkinson's disease (PD) is a neurodegenerative disorder that affects predominately dopaminergic neurons in a specific area of the brain called substantia nigra. While Parkinson’s itself is not...
17 January 2019 1,981 9 View
Cariprazine is a new generation antipsychotic. It is a dopamine D2- and D3-receptor partial agonist, with higher affinity for D3 receptors, as opposed to the D2 antagonism of most older...
16 November 2018 4,693 1 View
The effect of antipsychotics on the dopamine pathways in particular the nigro-striatal system is well known and documented as well as the short and long term extrapyramidal side effects. But we...
05 November 2017 3,106 10 View
Most consensus lines suggest you to repair them at 55mm. What are the arguments for and against this aggressive threshold and which percentage of patients don't need surgery since during the...
28 August 2017 9,977 2 View
The latest antidepressant vortioxetine has a new mechanism of action that combines direct 5-HT receptor modulation and SERT inhibition. In fact it is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist,...
31 July 2017 1,277 11 View
It seems we have no treatment disease-modifying for PD. That's been supposed for rasagiline, but no scientific evidence so far
15 July 2017 2,606 23 View
I'm looking any experience of EPS ( in particular Resting Tremor, Rigidity and Micrographia) developed following long-term treatment with paroxetine
04 July 2017 9,383 13 View
Amantadine and rimantadine appear to work, at least in part, by preventing newly synthesized viruses from being released from the host cell and are effective for reducing the duration of influenza...
01 January 1970 4,560 52 View
The 2019-nCoV belongs to Betacoronavirus, which also contains SARS-CoV and Middle East respiratory syndrome CoV (MERS-CoV). Several drugs, such as ribavirin, interferon, lopinavir-ritonavir,...
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