HBV and Malaria Endemicity overlaps in a number of geographical regions , a fact that might affect the malaria infection.
Yes there is overlap between them
Furthermore, we need to think about the vaccine and its effects on the infections
I agree , such a problem is likely to be solved through vaccination against one or both infections
Yes but we are still waiting for malaria vaccine
What can we do meanwhile? Is there any effect of malaria treatment on HBV?
I found an article that say HBV infection seems to modify the physiology of the host's immune system, stimulating increased inflammatory responses, reducing Plasmodium parasitemia and possibly diminishing parasite burden in patients living in endemic areas. Unfortunately, I didn't find any other article on the subject.
I have no experience with the treatment of malaria and HBV coinfection. I will try to find someone here in Brazil who has experience to help us in this question.
DOI: 10.1371/journal.pone.0019841
Dear Silvana D Pessoa.thank you very much for your contribution, however, a second group of researchers proposed a different proposal where they have spoke about the immune response against falciparum infected red blood cells might be suppressed by HBV carrier status
Article Relation between Hepatitis B Carrier Status and Antibody aga...
A third opinion concluded that HBV and malaria presumably have no effect on each other and evolve independently
Article Hepatitis B Virus Infection Does Not Significantly Influence...
Malaria and HBV coinfection is a true public health problem in developping countries where the both infectious diseases are endemic. Because, the liver damage increase and patients become inactive. The conseqences on the economic prodctivity are huge.
A new publication in this concern might be of help
Article Hepatitis B Hepatitis C virus and Malaria coinfection
Single-dose malaria treatment!
New treatment could save 500,000 lives and help 200 million people.
A study published today in Nature identifies new compounds to fight the malaria parasite,Plasmodium falciparum. Researchers from the Broad Institute of MIT and Harvard, headed by Stuart Schreiber, scoured a library of 100,000 chemical compounds for something that met the required criteria: targeting the parasite in a novel way and working during all three stages of its life (liver, blood, and transmission). These compounds were then tested on mice, and they successfully eradicated the malaria parasites during all three stages with one low dose. All of the 100,000 compounds in the library and the data from the team’s malaria screens are publicly available via theMalaria Therapeutics Response Portal (MTRP)...
https://www.researchgate.net/blog/post/single-dose-malaria-treatment
@Gasim, Malaria and Hepatitis B infection occur throughout the world endemic areas. Both infections represent key threat to
survival of the populace in the environment. They both have periods of high activity in the liver cells and affectation of the blood cells may lead to weakened immunity of an
individual thus increase chances for contracting other infections. Effects of malaria and hepatitis B infection on
liver cells lead to alterations in liver enzymes and serum protein due to hepatocelluler damage . Liver cells are unarguably infected by a hepatotropic HBV and also Plasmodium parasites for obvious reasons that it has some stages of its life cycle within the hepatocytes. Liver enzymes (aspartate amino transaminase, alanine amino transaminase), Alkaline phosphatase and serum proteins are diagnostic indices that determine its cellular membrane integrity and synthetic ability in liver dysfunction. Activities of liver enzymes increase in serum when there are factors responsible for cellular membrane damage.
Please find attached an article we published on this matter.
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