Ribosomes are thought to be sensors of temperature shocks for both heat & cold. that may be related to the adaptive ability to alter the regulatory network, best example of heat shocl proteins induction.
some paper suggested some nuclear changes an expansion of nuclear 45S pre-rRNA molecules in the mutant at 39 °C, suggesting an inhibition of its processing to 32S RNA. while, 45S and 32S precursor molecules in ts 422E are substantially undermethylated relative to the pre-rRNAs of wild-type BHK cells at 39 °C but identical at the permissive temperature (33 °C). The residual amount of mature 28S rRNA that appears in ts 422E cytoplasm at 39 °C is markedly methyl deficient. another paper found A decrease in the level of S21 at high temperature.