Yes mam, I have tried to search the review in Cochrane library but i am unable to find it . Can you please give me the title of the paper or the author's name
My understanding is that one cannot regularly find a synergy here.
F.e., see:
Eshghi SR, Bell GJ, Boulé NG. Effects of aerobic exercise with or without metformin on plasma incretins in type 2 diabetes.Can J Diabetes. 2013 ;37(6):375-380.
This study reveals several ways by which metformin and exercise therapies can affect each other. By increasing heart rate, metformin could lead to the prescription of lower exercise workloads. Furthermore, under the tested conditions, exercise interfered with the glucose-lowering effect of metformin.
https://www.ncbi.nlm.nih.gov › pmc
Metformin and Exercise in Type 2 Diabetes - PMC - NCBI
Research suggests metformin, a widely prescribed diabetes medication, may diminish the benefits of exercise when used in combination. In this study, however, metformin combined with exercise training, but not exercise alone, lowered proinsulin concentrations and increased insulin clearance in adults with prediabetes.Jul 18, 2017
https://journals.physiology.org › doi
Exercise training and metformin, but not exercise training alone ...