case: 10 years old boy with abdominal pain i epigastrium and reflux symtoms, the upper endoscopy shows eosinophilic esophagitis ( 60 eosinophils x HPF )
The boy is doing fine without symtoms after 5 months treatment with Omeprazol 20 mg x per dag. ( boy i 44 kg )
New biopsies are indicated after (PPI) therapy: if also pathology shows remission, I would consider continuing PPI long term
PPI is not the ideal treat
Local corticoids by inhailer is the best treatment ,
Repeat endoscopy with biopsy is often necessary. Several medications have been tried including corticosteroids. While these medicines reduce esophageal inflammation, when withdrawn, the disease recurs.
The best objective is to identify the type of food allergy associated and to follow-up an axclusion diet to thie special alllergen
Long-term use of PPI has been shown to be safe in adults; however, no studies in children are available.
Up to 70% of children with PPI-responsive EoE remain in histological and clinical remission on a low-dose maintenance treatment at 1-year follow-up, with adequate safety profile. Complete histological remission to an 8-week PPI trial was associated with higher probability of histological remission on maintenance therapy.[doi: 10.1097/MPG.0000000000001952.Multicenter Study. 2018 Aug;67(2):210-216.J Pediatr Gastroenterol Nutr
Long-term Treatment With Proton Pump Inhibitors Is Effective in Children With Eosinophilic Esophagitis
Carolina Gutiérrez-Junquera 1, Sonia Fernández-Fernández 2, M Luz Cilleruelo 1, Ana Rayo 2, Luis Echeverría 3, Belén Borrell 2, Enriqueta Román 1]
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