What is the correct equation to use when weighing the different chemical shifts of 1H and 15N nuclei in SOFAST HMQC spectra?

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Engi Hassaan

Thanks a lot for your answer. I noticed some papers multiply the δ1H squared and δ15N squared by 1/2 and then find the root square of their sum. Why multiply with 1/2?

Giovanni Bellomo

This publication may help you:

https://www.sheffield.ac.uk/polopoly_fs/1.393312!/file/shift_mapping_2013.pdf

I usually do: δavg=sqrt( 0.5*δ1H^2+0.5*(δ15N/5)^2)