The negative feedback idea is rather simple: When we inspire, bringing the diaphragm down, the pressure outside the atria drops, hence the venous return increases (the right atrium gets fuller). The heart 'thinks' (evolved to do this, God made it do it,...) 'I am too full of blood, I need to pump harder / faster to get empty, else I will get gorged and 'explode'. That is how I explain it to the students the first time I talk about it. Only later I go into the sensors and the full mechanism, as described in the literature. An excellent reference is...

Berne, R.M. and Levy, M.N., Cardiovascular Physiology, 6th ed. Mosby - Year Book Inc., St. Louis, 1992.

la explicacion es un tanto compleja, especialmente si no se tienen conocimientos basicos de anatomia y fisiologia, tanto del aparato respiratorio como del aparato cardiovascular. Al hacer una inspiracion profunda el diafragma desciende y comprime los grandes vasos abdominales, afectando la precarga cardiaca, de esa manera se disminuye el gasto cardiaco con la consiguiente disminucion de la tension arterial. Ademas juegan un papel importante los gases arteriales, los cuales tambien se ven afectados al realizar inspiraciones profundas.

From an integrative ancient concept called ”Bainbrain reflex“ to explain assess a volume of oxigened blood to central nervous system,is possible to access to comprenssive a point of view to begin to resolve your question. initially: consider Here a mathematical simple model of bainbrain reflex during a dynamic of little time periods

A.G. Ramakrishnan

It is a beautiful subject. Very good references are:

Circulatory physiology: cardiac output and its regulation. second edition, by A.C. Guyton, MD, C.E. Jones, MD, T.G. Coleman, PhD. Philadelphia, WB Saunders .1974.

http://www.comprehensivephysiology.com/WileyCDA/Section/id-420557.html

Heart rate control and mechanical cardiopulmonary coupling to assess central volume: a systems analysis

RICCARDO BARBIERI,1,2 JOHN K. TRIEDMAN,3 AND J. PHILIP SAUL1

1Department of Pediatrics, Medical University of South Carolina, Charleston,

South Carolina 29425; 2Department of Anesthesia and Critical Care, Massachusetts General Hospital/Harvard Medical School, Boston 02114; and 3Department of Cardiology, Children’s Hospital and Harvard Medical School, Boston, Massachusetts 02115

Am J Physiol Regulatory Integrative Comp Physiol 283:1210-1220, 2002. First published Aug 1, 2002; doi:10.1152/ajpregu.00127.2002

https://www2.palomar.edu/users/ccarpenter/haps%202008/pdfQKJDcoh1bc.pdf

Hi there,

As a person who teaches theoretical and clinical anatomy, I can recommend the following articles:

Article Autonomic and endocrine control of cardiovascular function

Article Regulation of Breathing and Autonomic Outflows by Chemoreceptors

Article The Unique Brain Anatomy of Meditation Practitioners: Altera...

Articles alone, however, will not be sufficient. For concise, correct and optimal results in your research efforts, check out:

https://www.thieme.com/books-main/anatomy/product/3581-atlas-of-anatomy

https://www.thieme.com/books-main/physiology/product/3599-principles-of-medical-physiology-2-e

or alternatively:

https://www.thieme.com/books-main/physiology/product/1998-color-atlas-of-physiology

I hope that helps :)