The management of slit ventricle syndrome is difficult and challenging. Various treatment options have been proposed, and include:
1. Observation.Usually limited to minimally symptomatic patients
2. Anti-migraine medicines.
3. Shunt revision. - Change the ventricular catheter, Change the shunt valve like add siphon controlling device (SCD), Programmable valve with or without SCD. Converting to a lumboperitoneal shunt.
4. Temporarily blocking the flow of the shunt (via "externalization" of the shunt) in order to expand the ventricles.This should be done with ICP monitoring due to the risk of coma. Many patients have aqueductal stenosis, and therefore are candidates for endoscopic third ventriculostomy (ETV).In some cases, a special shunt configuration draining both the ventricles and the cisterns (space around the brain) can equalize the inner and outer brain pressures, thus reducing the chance of producing slit ventricles again.
5. Subtemporal decompression.This procedure is rarely performed because improvements, if any, are typically short-lived.