A common feeling in the skin or below the skin- tissues . Pain arises due to a force applied beyond our tolerance externally or internally through any ingrowth inside. Illness is just getting rid of pain / reduction in temperature in our body.
Pain is the interpretation of nociception by consciousness. Consciousness is generated by the cerebral cortex. It interprets sensory information and combines it with memory mechanism information to generate awareness. Pain is harmful because it elevates sympathetic nervous activity that inhibits organ perfusion. Consciousness regulates nociception via inhibitory corticofugal signals that descend from the cerebral cortex to spinal cord nociception pathways. For a detailed presentation read my book called “50 Years Lost in Medical Advance: The Discovery of Hans Selye’s Stress Mechanism” that is available via Amazon.com
Fever is a manifestation of harmful stress mechanism hyperactivity that causes disease. The stress mechanism is hyperactivated by combinations of tissue disruption and nervous activity, so simply removing the hypothalamus from your body would not eliminate fever.
If you’d like to learn about stress theory and the stress mechanism, try reading the attached papers or buy my book called “50 Years Lost in Medical Advance: The Discovery of Hans Selye’s Stress Mechanism” via Amazon.com
Stress is multitasking and emotions experienced doing so. By multitasking I mean multiple events , all leading to feelings of grief. This state is stress. We are in stress in the mad pursuit of success, money and people dependent on us. If we take this grief lightly like a monster, we are good at managing strees. Our book Bhagavadgita says, the person who can master stress or treat both happiness and grief equal, is a mature person . Thank you for the offer. If I get scope, I shall definitely read your books.
“Pain is a pesky part of being human, I've learned it feels like a stab wound to the heart, something I wish we could all do without, in our lives here. Pain is a sudden hurt that can't be escaped. But then I have also learned that because of pain, I can feel the beauty, tenderness, and freedom of healing. Pain feels like a fast stab wound to the heart. But then healing feels like the wind against your face when you are spreading your wings and flying through the air! We may not have wings growing out of our backs, but healing is the closest thing that will give us that wind against our faces.”
Some people ask where is the technology which existed during the time India invented 0. I say we made a mistake of duplicating invention which they did not. We have just one book, Bhagavad gita, enough to invent.
Pain is an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. -IASP 2020
Most people equate “stress” with emotional angst and assume that this is somehow harmful to health, but there has never been an explanation of how painful emotions can affect health. The mammalian stress mechanism (MSM) explains how emotional adversity harms health and confers a broader and more effective definition of stress. The MSM normally functions unobtrusively to repair tissues and regulate organ function in accord with environmental stresses including hunger, extreme cold, excessive heat, trauma, surgery, harmful radiation, and toxic substances as well as emotional adversity. When the sum total of environmental stresses causes harmful stress mechanism hyperactivity, the MSM begins to consume, waste, and deplete its substrates and produce harmful excesses of its products. This manifests as disease.
Emotional stress is very powerful. It operates in conjunction with memory, the dreaming mechanism, and consciousness to enable the mechanism of “fight or flight” that subconsciously and automatically identifies dangerous environmental circumstances and induces “pre-emptive" fear and anxiety that elevates sympathetic nervous activity to facilitate fight or flight, and optimize survival. The sympathetic nervous hyperactivity closes the capillary gate and temporarily inhibits microvascular perfusion of nonessential organs such as the bowel. It also releases “stress hormones” such as glucagon that releases glucose into blood to facilitate muscle activity to facilitate fight or flight. The fight or flight mechanism is an emergency mechanism that enhances survival, but the fear, anxiety, and sympathetic nervous hyperactivity becomes harmful or even lethal if it is severe and prolonged, even in the absence of physical injury or other forms of stress.
Nociception is nervous activity generated by nervous sensors in the skin and internal organs that detect tissue distortion and tissue disruption. These sensors are called “nociceptors.” They generate “nociception” that is transmitted to the spinal cord via peripheral sensory nerves. The spinal cord transmits nociception to sympathetic ganglia in the thorax and abdomen that innervate the internal organs with sympathetic nerve endings. The spinal cord also conducts nociception signals to the cerebral cortex, which interprets the nociception as “pain,” which exaggerates ganglionic sympathetic nervous activity.
The cerebral cortex generates consciousness, which interprets sensory information including sight, sound, taste, smell and nociception, and integrates this sensory information with memory and emotion to enable awareness of environmental circumstances.
Consciousness inhibits spinal cord nociception pathways via descending (“corticofugal”) pathways from the cortex to the spinal cord. This enables consciousness to suppress the perception of pain to facilitate fight or flight.
Pain is the perception of nociception by consciousness.
Anesthesia is hypnotic agents that abolish consciousness in a dose related manner to inhibit the perception of nociception as pain by consciousness.
Analgesia is the direct inhibition of nociception pathways by opioids or local analgesic nerve blocks.
Neither anesthesia alone nor analgesia alone can effectively prevent harmful surgical nervous hyperactivity and optimize surgical outcome. Combinations of anesthesia and analgesia are essential to minimize harmful surgical nervous stimulation and optimize surgical outcome.