why would you research this when the answer is available ... as well as the cure for diabetes type II .......
Elevated/abnormal/uncontrolled blood sugar i.e post postprandial hyperglycemia marks its beginning.
insulin resistance and persistent hyperglycemia, both are necessary to distinguish type II.
The parameters of the so called Syndrome X namely hyperglycaemia, hypertriglyceridemia, hypertension and obesity can be used as markers for the induction of type 2 DM. Lack of antibodies in diagnosing type 1 DM can also be used as a guidance.
http://care.diabetesjournals.org/content/27/3/813.short.
Above is a nice article answering your question
Clinically, there are 3 parameters, high glucose, Insulin resistance and abnormal glucose tolerance test, considering only the glucose will give you the diagnosis for diabetes but wont let you know what kind of I or II. So high glucose most to be evaluated together to insulin resistance and tolerance test.
The pathology of type 2 diabetes is complex and is different from that of type 1 diabetes. One example of a type 2 diabetes animal model is the high-
fat diet-fed, streptozotocin (HFD/STZ)-treated rat model. First, one has to understand the metabolic profile and pathology involved.As mentioned by Modesto Rojas, in this model, you can measure hyperinsulinemia, insulin resistance and/or glucose intolerance in addition to reduction in functional b-cell mass.
The differences between Type I and II Db is that in Db type II the pancreas still can produce insulin, so measurement of endogenous insulin is an excellent parameter
Type 2 diabetes is apparently also the result of destroyed enzyme functions, especially in the metabolism of aldehydes.
In the head-space-blood alcohol test after consumption of carbohydrates, damage caused by enzyme inhibitors is visible before diabetes type 2 is diagnosed.
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