What is a suitable purification method for big dextrans (> 2000 kDa) beside size exclusion chromatography?

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Naser Jawad Kadhum Popular answer

I gree with Adam B Shapiro

Adam B Shapiro

Capillary electrophoresis is not a preparative technique because the capillary diameter is so small.

What are you trying to separate, and why not use size exclusion?

Naser Jawad Kadhum

Article SEC Separation of Polysaccharides Using Macroporous Spherica...

Jan-Dirk Wehland

Thank you for your help! I try to separate big dextrans (~2000kDa) coupled to proteins. I just want to know if there are any alternatives for SEC. Of course, this is the means of choice and i will go ahead to test SEC with other resins etc. Separation on an analytical scale would help as well... Thank you and have a nice day. Best, Jan

If you want to use capillary electrophoresis analytically, it might work best to use capillary gel electrophoresis. But I'm wondering what you will do about detection.