Genes help man escape Alzheimer’s
Scientists identify nine genetic variants that could have helped a man to avoid dementia for at least two decades longer than expected...
"A man with a mutation in a gene called PSEN2, which causes the brain to produce versions of the amyloid protein that are prone to forming the hallmark sticky plaques of Alzheimer’s disease, has reached his mid-70s with no cognitive decline. All of the man’s family members with the mutation had developed dementia around age 50. Scans revealed that the man’s brain was full of amyloid plaques. But it had very little abnormal tau — another protein that forms tangled threads inside neurons. Researchers found that the man has nine genetic variants that weren’t present in his relatives who had the PSEN2 mutation and that might have protected him from the disease."
https://www.nature.com/articles/d41586-025-00398-4
17 Ways to Cut Your Risk of Stroke, Dementia and Depression All at Once
A new study identified overlapping factors that affect your odds of developing these brain diseases late in life...
https://www.nytimes.com/2025/04/23/well/dementia-stroke-depression-prevention.html?
https://jnnp.bmj.com/content/early/2025/03/21/jnnp-2024-334925.long
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