1) When the glass vial gets transparent again
2) when the glass vial doesn't smell like soap or an organic solvent.
good luck Reto
Dear Mr Reshabh
Cleaning of glass wire or apparatus differ from cleaning of machine or container or floor.cleaning operation as defined is absence of dirt , more details are needed to get
satisfying answer, better give more details
regards
Dear Rishabh,
Please find attached article which might be helpful to you.
Regards,
Abhishek
Cleaning validation is the documentary evidence that the cleaning methods are enough to assure that inter products contamination can be prevented.
The so called cleaned material should not leave any stain,colour,residue and react with anything.
In industry we must make sure that even insoluble substance are cleaned or more specifically removed from the surface so that traces of the substance shall not move from one product to another.
Also it a regulatory requirement to perform cleaning validation.
Dear Rishabh
from my experience in the food industry
there should be a documented description for the cleaning process of each item
How to clean - what detergent or cleaning, or sanitation materiel you will use
when to clean
who will clean
who will check up cleaning operation and how
some times you need chemical test
sometimes you need microbiological test to avoid both mix up - contamination
this route or alike should be followed and any step should be documented and records kept-
corrective actions case of defects should be considered
regards
If you feel that your material has been cleaned sufficiently, clean it three times more to be sure.
In pharmaceutical industry we need to be sure that traces of previous products don't contaminate the next products. Thus we have to perform the cleaning validation to be sure that even invisible particles were removed for the product that is more prone to microbial contamination, insoluble or very hard to clean.
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