The Question is a good one and no one have decisive answer .

Both antibiotics and mycotoxins are secondary metabolites. Antibiotics serve the producing fungus or bacteria in competing with others. Mycotoxins has no known role, however, they might weaken the receiving host thus providing a higher chance of proliferation.

Mycotoxins certainly have pharmacological/toxicological properties. Aflatoxin is carcinogenic, zearalenone has estrogenic activity etc.

I agree with Abdelraouf A. Elmanama ..

but need reference

Antibiotic and mycotoxins had many similarities in structure and metabolic roles.

mycotoxins cannot kill bacteria or fungi.

They are carcinogenic chemical compunds released by growing fungi.

Mycotoxins are not man made and only some are carcinogenic!

Mycotoxins are naturally produced from fungus due to wet environment favoring toxins production while antibiotics are man-made and acts against harmful organisms in the body, lowing the immunity of the host. Access of both are dangerous, causing organism resistance and carcinogenicity.

Penicillium fungi are the original source of penicillins!

Patulin was in the beginning considered to be a promising antibiotic, but is now only considered to be a mycotoxin.

See wikipedia/patulin

While all mycotoxins are of fungal origin, not all toxic compounds produced by fungi are called mycotoxins. The target and the concentration of the metabolite are both important. Fungal products that are mainly toxic to bacteria (such as penicillin) are usually called antibiotics. Fungal products that are toxic to plants are called phytotoxins by plant pathologists (confusingly, the term phytotoxin can also refer to toxins made by plants; see Graniti [93] for a cogent discussion of the etymology of phytotoxin and its use in plant pathology). Mycotoxins are made by fungi and are toxic to vertebrates and other animal groups in low concentrations. Other low-molecular-weight fungal metabolites such as ethanol that are toxic only in high concentrations are not considered mycotoxins Article Mycotoxins

Abdelraouf A. Elmanama bdelraouf A. Elmanama

Thanks for all readers and who answered My question. But we need information or research paper explain different to show it for researchers. Regards

Mycotoxins are secondary metabolites produced by microfungi that are capable of causing disease and death in humans and other animals. Because of their pharmacological activity, some mycotoxins or mycotoxin derivatives have found use as antibiotics, growth promotants, and other kinds of drugs; still others have been implicated as chemical warfare agents. This review focuses on the most important ones associated with human and veterinary diseases, including aflatoxin, citrinin, ergot akaloids, fumonisins, ochratoxin A, patulin, trichothecenes, and zearalenone.

Look at the link Antibiotics produced by Fungi?

https://www.jstor.org/stable/4353729?seq=1#page_scan_tab_contents

Article On the origin of antibiotics and mycotoxins

Article Mycotoxins

Article On the origin of antibiotics and mycotoxins

Antibiotics kill bacteria but natural mycotoxin can’t.

Mycotoxins are secondar use as antibiotics, growth promotants, and other kinds of drugs; still others have been implicated as chemical warfare agents. This review focuses on the most important ones associated with human and veterinary diseases, including aflatoxin, citrinin, ergot akaloids, fumonisins, ochratoxin A, patulin, trichothecenes, and zearalenone. y metabolites produced by microfungi that are capable of causing disease and death in humans and other animals. Because of their pharmacological activity, some mycotoxins or mycotoxin derivatives have found

While all mycotoxins are of fungal origin, not all toxic compounds produced by fungi are called mycotoxins. The target and the concentration of the metabolite are both important. Fungal products that are mainly toxic to bacteria (such as penicillin) are usually called antibiotics. Fungal products that are toxic to plants are called phytotoxins by plant pathologists (confusingly, the term phytotoxin can also refer to toxins made by plants; see Graniti [93] for a cogent discussion of the etymology of phytotoxin and its use in plant pathology). Mycotoxins are made by fungi and are toxic to vertebrates and other animal groups in low concentrations. Other low-molecular-weight fungal metabolites such as ethanol that are toxic only in high concentrations are not considered mycotoxins