Dear Syeda

I suggest that you read publications from the following authors:

Lochner A

Huisamen B

Salie R

https://doi.org/10.1186/s12933-014-0109-8

doi: 10.1007/s10557-010-6271-7.

doi:  10.1186/s12899-017-0030-y

Melatonin alos provides protection against ROS.

thank you sir, i'll read these

Dear Syeda,

Cyclosporin A can be used as a positive control for reduced infarct size (see Lim et al. DOI:10.1111/j.1476-5381.2011.01691.x ), but I don't know if it is possible to administer i.g. in a mouse model.

Dietary nitrite can reduce infarct size when given one week prior to I/R via drinking water (Bryan et al. PNAS 2007)

Article Dietary nitrite supplementation protects against myocardial ...

Thank you Lars Michel .

i was also wondering about i.g. route for CsA.

i will try dietary nitrite supplements.