25 April 2018 3 8K Report

As it is our pilot study we would like to use the easy and cheap method.

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How to link TRIZ philosophy and TRIZ Tools ?

The idea is to write a paper about the link between TRIZ tools and TRIZ philosophy and explore possibilities to develop new tools in regard to technology development and use of AI.

17 September 2023 9,088 0 View

What if one main effect of a 2 ways Manova is not significant but follow up ANOVAS show significant effects?

I am currently working on the results of a 2x2 design. I used a MANOVA and there was only one significant main effect of one condition (the main effect from the other condition is unsignificant...

20 March 2023 830 3 View

How to identify exogenous DNA sequences in PacBio sequencing datasets?

Hello, I have PacBio raw sequencing datasets from cells infected with Trypanosoma cruzi. We're trying to identify whether the protozoan integrates kDNA sequences of ~12bp size in the host cells'...

21 August 2022 6,485 2 View

Could anybody please tell me what makes siRNA-based therapeutics that costly and is there any prognosis that the price will drop in the future?

To date, FDA has approved in total 3 siRNA-based drugs since 2017. According to official sources Patisiran (Onpattro) - the first siRNA-based therapeutic approved by FDA, costs over $450,000 per...

14 October 2021 9,734 3 View

How to perform Principal Component Analysis on form with R ?

I would like to explore my data by plotting a Principal Component Analysis on form rather than only shape, similar to the procedure of Mitteroecker et al. (2004) in Journal of Human Evolution....

24 June 2020 4,508 7 View

How to assess the stability and bundedness of a steady N.-S. scheme?

The Von Neumann stability analysis is used to asses the stability of a transient scheme but cannot be used for a time-independent one. How do I asses the stability and boundedness of a steady...

19 June 2020 514 0 View

Is it statistically allowed to form a quotient ofrelative values and mean values to get a KPI??

Dear community, i conducted a SERVIMPERF customer satisfaction study and retrieved 21 customer ratings for perceived importance and satisfaction with 15 items. In order to prioritize the items...

20 February 2020 5,236 0 View

Approach to cluster concepts of qualitative research?

Dear community, does anyone have any suggestion which approach or method could be used during scientific writing, if one has a variety of qualitative concepts and needs to reduce the amount of...

06 December 2018 2,828 2 View

How to validate a deletion?

So I deleted an exon of a gene in a cell line using CRISPR. The region deleted is around 1500bp. I isolated colonies, extracted DNA and ran a PCR with primers designed upstream and downstream of...

05 December 2018 3,573 2 View

Suitable Online-Tool for AHP-based Surveys?

Dear community, does anybody have experience with any online tools or services to conduct AHP-based surveys? That means the question design should be some kind of matrix and additionally allow...

24 November 2018 8,099 5 View

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